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Publications

GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control

Kelsey L Hickey, Kimberley Dickson, J Zachery Cogan, Joseph M Replogle, Michael Schoof, Karole N D’Orazio, Niladri K Sinha, Jeffrey A Hussmann, Marco Jost, Adam Frost, Rachel Green, Jonathan S Weissman*, Kamena K Kostova* 2020. Molecular Cell, DOI

CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides.

Kamena K Kostova, Kelsey L Hickey, Beatriz A Osuna, Jeffrey A Hussmann, Adam Frost, David E Weinberg, Jonathan S Weissman 2017. Science 357 (6349), 414-417

Stage-specific sensitivity to p53 restoration during lung cancer progression.

David M Feldser, Kamena K Kostova, Monte M Winslow, Sarah E Taylor, Chris Cashman, Charles A Whittaker, Francisco J Sanchez-Rivera, Rebecca Resnick, Roderick Bronson, Michael T Hemann, Tyler Jacks 2010. Nature 468 (7323), 572

Complete deletion of Apc results in severe polyposis in mice.

Ann F Cheung, Alia M Carter, Kamena K Kostova, Joseph F Woodruff, Denise Crowley, Roderick T Bronson, Kevin M Haigis, Tyler Jacks 2010. Oncogene 29 (12), 1857

ZNF574 is a Quality Control Factor For Defective Ribosome Biogenesis Intermediates

Jared F. Akers, Adrian Bothe, Hanna Suh, Carmen Jung, Zachary Stolp, Tanushree Ghosh, Liewei Yan, Yuming Wang, Tarabryn Grismer, Andreas Reyes, Tianyi Hu, Shouling Xu, Nenad Ban, Kamena K. Kostova. bioRxiv. 2024. Apr 29:2024.04.26.591394. doi: 10.1101/2024.04.26.591394.